Human tonsil: immunohistochemical staining for CD56. Note the NK cells and CD4/CD8 double positive T cells show a weak to moderate and distinct membrane staining reaction while the majority of lymphocytes are unstained. CD56: clone CD564

CD56 (NCAM)

cd56-ncam

Antigen Background

The neural cell adhesion molecules are a family of closely-related cell surface glycoproteins thought to play a role in embryogenesis, development and contact-mediated interactions between neural cells. The CD56 antigen (NCAM) consists of four major isoforms generated by differential splicing of the RNA transcript from a single gene located on chromosome 5. The CD56 antigen is expressed on neurons, astrocytes, Schwann cells, NK cells and a subset of activated T lymphocytes.

Disclaimer

CD56 (NCAM) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • CD56-504-L-CE
    1ml NCL-L-CD56-504
    CD564
    Liquid Concentrate
    P (HIER)
  • PA0191
    7ml CD56 Bond RTU Primary
    CD564
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

CD56-504-L-CE
Hematopathology
CD564
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0191
Hematopathology
CD564
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

CD56-504-L-CE
PA0191

Resources

Resources

Antigen Background

The neural cell adhesion molecules are a family of closely-related cell surface glycoproteins thought to play a role in embryogenesis, development and contact-mediated interactions between neural cells. The CD56 antigen (NCAM) consists of four major isoforms generated by differential splicing of the RNA transcript from a single gene located on chromosome 5. The CD56 antigen is expressed on neurons, astrocytes, Schwann cells, NK cells and a subset of activated T lymphocytes.

Disclaimer

CD56 (NCAM) is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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