Diffuse large B cell lymphoma: immunohistochemical staining for CD43. Note the intense staining of malignant CD43: clone MT1

CD43

cd43

Antigen Background

The CD43 antigen is expressed on the membrane and in the cytoplasm of T cells and cells of myeloid lineage. The molecule itself exhibits molecular weight heterogeneity with bands of 90 to 140 kD observed on SDS-PAGE between different cell lines. Cells expressing the CD43 antigen are reported to include normal and neoplastic T cells. A small proportion of B cell chronic leukemias and diffuse large B cell lymphomas are also reported to express CD43 antigen.

Product Specific Information

Enzyme pretreatment may enhance staining with clone MT1 in some cases.

Disclaimer

CD43 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • MT1-L
    1ml NCL-L-MT1
    MT1
    Liquid Concentrate
    P
  • PA0938
    7ml CD43 Bond RTU Primary
    MT1
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

MT1-L
Hematopathology
MT1
Liquid Concentrate
No
P
Mono
Mouse
Research Use Only
1ml
PA0938
Hematopathology
MT1
BOND RTU
No
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
7ml

Documents

Documents

MT1-L
PA0938

Resources

Resources

Antigen Background

The CD43 antigen is expressed on the membrane and in the cytoplasm of T cells and cells of myeloid lineage. The molecule itself exhibits molecular weight heterogeneity with bands of 90 to 140 kD observed on SDS-PAGE between different cell lines. Cells expressing the CD43 antigen are reported to include normal and neoplastic T cells. A small proportion of B cell chronic leukemias and diffuse large B cell lymphomas are also reported to express CD43 antigen.

Product Specific Information

Enzyme pretreatment may enhance staining with clone MT1 in some cases.

Disclaimer

CD43 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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