Human tonsil: immunohistochemical staining for CD19. Note membrane staining of B cells. CD19: clone BT51E

CD19

cd19

Antigen Background

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein present on the surface of B lymphocytes and follicular dendritic cells of the hematopoietic system. CD19 is a crucial regulator in B cell development, activation and differentiation. On B cells, CD19 associates with CD21, CD81 and CD225 (Leu-13) forming a signal transduction complex. CD19 is expressed from the earliest recognizable B cell lineage stage, through development to B cell differentiation but is lost on maturation to plasma cells.

CD19 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

  • CD19-163-L-CE-H
    0.5ml NCL-L-CD19-163
    BT51E
    Liquid Concentrate
    P (HIER)
  • CD19-163-L-H
    0.5ml NCL-L-CD19-163
    BT51E
    Liquid Concentrate
    P (HIER)
  • CD19-163-L
    1ml NCL-L-CD19-163
    BT51E
    Liquid Concentrate
    P (HIER)
  • CD19-163-L-CE
    1ml NCL-L-CD19-163
    BT51E
    Liquid Concentrate
    P (HIER)
  • PA0843
    7ml CD19 Bond RTU Primary
    BT51E
    BOND RTU
    P (HIER)

Product Specifications

Product Specifications

CD19-163-L-CE-H
Hematopathology
BT51E
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
CD19-163-L-H
Hematopathology
BT51E
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
Research Use Only
1ml
CD19-163-L
Hematopathology
BT51E
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
Research Use Only
1ml
CD19-163-L-CE
Hematopathology
BT51E
Liquid Concentrate
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use
1ml
PA0843
Hematopathology
BT51E
BOND RTU
Yes
P (HIER)
Mono
Mouse
In Vitro Diagnostic Use

Documents

Documents

CD19-163-L-CE-H
CD19-163-L-H
CD19-163-L
CD19-163-L-CE
PA0843

Resources

Resources

Antigen Background

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. It is a single chain glycoprotein present on the surface of B lymphocytes and follicular dendritic cells of the hematopoietic system. CD19 is a crucial regulator in B cell development, activation and differentiation. On B cells, CD19 associates with CD21, CD81 and CD225 (Leu-13) forming a signal transduction complex. CD19 is expressed from the earliest recognizable B cell lineage stage, through development to B cell differentiation but is lost on maturation to plasma cells.

CD19 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.

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