1q21

1q21

1q21 / SRD (1p36)

Frequent loss of heterozygosity (LOH) on the short arm of chromosome 1 (1p) has been reported in a series of human malignancies. The combination with the potentially amplified 1q21 region allows to detect deletions at 1p36 and gain of 1q21 in a single FISH assay.

1q21 / 8p21

Amplifications of 1q21 are concurrent with dysregulated expression of MAF, WHSC1/FGFR3, or del(13) and represent an independent unfavorable prognostic factor. Allelic losses of the chromosome 8p21-22 have been reported as a frequent event in several cancers.

References:

Cremer et al. 2005, Genes Chrom Cancer, 44: 194-203.
Shaughnessy J., 2005, Hematology, 10 suppl 1: 117-126.

  • KBI-10503
    1q21 / 8p21
  • KBI-10507
    1q21 / SRD (1p36)
  • KI-10503
    1q21 / 8p21
  • KI-10507
    1q21 / SRD (1p36)

Product Specifications

Product Specifications

KBI-10503
Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Deletion Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent
KBI-10507
Hematopathology
In Vitro Diagnostic Use
10 test
Dual Color > Red, Green
Cells
Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent
KI-10503
Research
Research Use Only
10 test
Dual Color > Red, Green
Cells
Deletion Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent
KI-10507
Research
Research Use Only
10 test
Dual Color > Red, Green
Cells
Amplification
Gene Region-Specific
Fluorescent
Ready-to-Use
Manual Reagent

Documents

Documents

KBI-10503
KBI-10507
KI-10503
KI-10507

Resources

Resources

1q21 / SRD (1p36)

Frequent loss of heterozygosity (LOH) on the short arm of chromosome 1 (1p) has been reported in a series of human malignancies. The combination with the potentially amplified 1q21 region allows to detect deletions at 1p36 and gain of 1q21 in a single FISH assay.

1q21 / 8p21

Amplifications of 1q21 are concurrent with dysregulated expression of MAF, WHSC1/FGFR3, or del(13) and represent an independent unfavorable prognostic factor. Allelic losses of the chromosome 8p21-22 have been reported as a frequent event in several cancers.

References:

Cremer et al. 2005, Genes Chrom Cancer, 44: 194-203.
Shaughnessy J., 2005, Hematology, 10 suppl 1: 117-126.

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