p63 Protein

Antigen Background

p63 is a type II integral membrane protein predominantly localized in the rough endoplasmic reticulum. p63 is reported to be expressed in a number of normal tissues including proliferating cells of the epithelium, cervix, urothelium and prostate. p63 is also reported to be expressed in most poorly differentiated squamous cell carcinomas.

Disclaimer

p63 Protein is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.