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Antigen Background
This monoclonal antibody recognizes both wild-type and mutant forms of human p53 protein under denaturing and non-denaturing conditions. The epitope recognized by clone DO-7 can be destroyed by prolonged fixation in buffered formalin. The heat-induced epitope retrieval technique may improve staining in some cases.
Disclaimer
p53 Protein is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
