CD15

Antigen Background

CD15 antigen, also known as X-hapten, is reported to be expressed on 90% of circulating human granulocytes, 30-60% of circulating monocytes and is absent from normal lymphocytes. The CD15 antigen is also expressed on Reed-Sternberg cells of Hodgkin's disease and some leukemias.

Disclaimer

CD15 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.