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Antigen Background
Caveolin-1 は、カベオラの主な構成成分の一つで、いくつかのシグナル伝達を調整する分子として機能していると考えられています。平滑筋、含脂肪細胞、内皮細胞などの末期的に分化した間葉系細胞に強く発現が認められ、繊維芽細胞や膵臓癌でも陽性が報告されています。Caveolin-1 は、肉腫のようないくつかの悪性腫瘍において腫瘍抑制因子として機能している可能性が示唆されています。
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