SS18 (18q11) Break probe hybridized to patient material showing translocation of the SYT (SS18) gene region at 18q11 (1RG1R1G).
SS18 (18q11) Break probe hybridized to patient material showing translocation of the SYT (SS18) gene region at 18q11 (1RG1R1G).
IVD SS18 Break
The characteristic chromosomal abnormality in Synovial Sarcoma t(X;18)(p11.2;q11.2) is present in 90% of the patients. This translocation results in the fusion of the synovial sarcoma translocation, chromosome 18 (SS18) gene to either of two distinct genes, SSX1 or SSX2, located on the X chromosome. The SS18 (18q11) Break probe is optimized to detect translocations involving the SS18 gene region at 18q11 in a dual-color, split assay on paraffin embedded tissue sections.
References: Kawai et al, 1998, NEJM, 338; 153-160. Surace et al, 2004, LabInvest., 84; 1185-1192.
Prodotti
Prodotti
KBI-10713
ON SYT (18q11) Break
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