Advancing Cancer Diagnostics, Improving Lives
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Description de l'antigène
L'antigène Ki67 est une protéine nucléaire exprimée dans toutes les phases actives du cycle cellulaire (G1, S, G2 et mitose), mais absente dans les cellules en repos (G0).
Au contraire de beaucoup d'autres protéines associées au cycle cellulaire, l'antigène Ki67 est toujours absent dans les cellules inactives et n'est pas détectable pendant les processus de réparation de l'ADN.
La présence de l'antigène Ki67 est donc strictement associée au cycle cellulaire et limitée au noyau, ce qui suggère un rôle important dans le maintien et/ou la régulation du cycle de division cellulaire.
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