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Description de l'antigène
Le contenu en récepteurs des œstrogènes (ER) du tissu mammaire cancéreux est un paramètre important dans le pronostic et la prédiction de la réponse à la thérapeutique hormonale. L'introduction d'anticorps monoclonaux anti-ER hautement spécifiques a permis à la détermination du statut des récepteurs des tumeurs du sein d'être effectuée en routine dans les laboratoires d'histopathologie.
Le clone 6F11 est dirigé contre la chaîne alpha entière du récepteur des œstrogènes humain, située dans le noyau des cellules normales et néoplasiques ER-positive. Le clone 6F11 a été abondamment testé.
Les NCL-ER-6F11/2 et NCL-L-ER-6F11/2 sont des options plus économiques pour les utilisateurs haut-débit du clone 6F11.
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