Neurofilament 200kD

Antigen Background

Neurofilaments constitute the main structural elements of neuronal axons and dendrites. Neurofilaments are composed of three major subunits referred to as the neurofilament triplet, with molecular weights of 68 kD, 160kD and 200 kD. Within tumors, only neoplastic cells of neural origin or those exhibiting neuronal differentiation, have been reported to express neurofilaments.

Disclaimer

Neurofilament 200kD is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.