MECOM t(3;3);inv(3) (3q26) Break probe hybridized to patient material showing a rearrangement involving the MECOM gene region at 3q26 (1RG1R1G). Image kindly provided by Dr. Reed, London.
MECOM t(3;3);inv(3) (3q26) Break probe hybridized to patient material showing a rearrangement involving the MECOM gene region at 3q26 (1RG1R1G). Image kindly provided by Dr. Reed, London.
RUO MECOM Break Triple color
The MECOM t(3;3); inv(3)(3q26) Break Triple-Color FISH probe is optimized to detect the inversion of chromosome 3 involving the MECOM (previously known as EVI) gene region at 3q26 in a dual-color, split assay on metaphase/interphase spreads, blood smears and bone marrow cells. By using a third color breakpoint variations can also be easily observed.
References: De Braekeleer et al, 2011, Anticancer Res, 31; 3441-3448. Levy E. et al, 1994, Blood, 83; 1348-1354. Cui W. et al, 2011, Am J Clin Pathol, 136; 282-288. Wieser R et al, 2003, Haematologica, 88; 25-30. De Melo V. et al, 2007, Leukemia aop, 13 Sep, 1-4. Shearer B. et al, 2010, Am J Hematol, 85:569-574.
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