5q- (5q31; 5q33) / TERT (5p15)Triple-Color probe hybridized to a normal metaphase (2R2G2B).
5q- (5q31; 5q33) / TERT (5p15)Triple-Color probe hybridized to a normal metaphase (2R2G2B).
RUO - 5q- Triple-Color
The 5q- specific FISH probe is optimized to detect copy numbers at the CDC25C / EGR1 gene region at 5q31 and the CSF1R / RPS14 gene region at 5q33 simultaneously in a dual-color assay. The triple-color probe provides in addition to the two critical regions a control in blue targeting the TERT (previously known as hTERT) gene region at 5p15.
References: Boultwood J e.a., Blood 2002, 99; 4638-4641. Zhao N e.a., PNAS 1997, 94; 6948-6953. Wang e.a., Haematologica 2008, 93; 994-1000. Ebert BL e.a., Nature 2008, 451; 335-339. Mohamedali A and Mufti GJ, Brit J Haematol 2008, 144; 157-168.
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