Human Tonsil: Immunohistochemistry staining of TIM-3. TIM-3: clone EPR22241
Human Tonsil: Immunohistochemistry staining of TIM-3. TIM-3: clone EPR22241
TIM-3
Antigen Background TIM-3 (T-cell Immunoglobulin and Mucin Domain-Containing 3, Hepatitis A Virus Cellular Receptor, HAVCR2). TIM-3 is a Type I transmembrane that can be expressed on both tumour and immune cells. It is expressed on multiple immune cells, including type 1 T helper (Th1) cells, Th17 and CD8+ T cells, Tumour Infiltrating Lymphocytes, regulatory T cells (Tregs) and innate immune cells.
Disclaimer TIM-3 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
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